Transforming visual information to spatial maps
How do place cells learn about the environment? It has long been known that the place cells use visual information such as landmarks and optic flow. But how the visual information is being transformed from an representation as seen by the eyes (egocentric) into representation of the world (allocentric) in the hippocampal formation is as yet unknown. By simultaneously recording from a large population of neurons in the two areas we are addressing some of these questions.
Saleem, Harris, Carandini, Submitted
Vision during movement
Vision is one of the most commonly studied areas of the brain. However, our understanding of vision is limited to when one is sitting in a fixed spot. Little is know about vision during movements such as walking or navigation.
Saleem et al, Nat Neuro, 2013
Ayaz et al, Curr Biol, 2013
Saleem et al, Submitted
Innate visual behaviour
G De Franceschi, T Vivattanasarn, A B Saleem*, S G Solomon*, Current Biology, 2016
Memory replay and sleep
H F Olafsdottir*, C J Barry*, A B Saleem, D Hassibis, H Spiers, Hippocampal place cells construct reward related sequences through unexplored space. eLife (2015).
Neural coding in populations
With new technologies we now are able to record simultaneously from large populations of neurons from single or multiple areas. Part of our research focus is to understand how signals regarding the world are encoded by populations of neurons.
Rossant, Kadir, et al,
Saleem, et al, Nat Neuro, 2013;
Benucci et al, Nat Neuro, 2013;
Busse et al, J Neurosci, 2011;
Schovinck et al, J Neurosci., 2015