Research

(DiI stain of electrode tracks in visual cortex and Hippocampal area CA1 , from Saleem et al. in  prep.)

(DiI stain of electrode tracks in visual cortex and Hippocampal area CA1 , from Saleem et al. in  prep.)

Transforming visual information to spatial maps

How do place cells learn about the environment? It has long been known that the place cells use visual information such as landmarks and optic flow. But how the visual information is being transformed from an representation as seen by the eyes (egocentric) into representation of the world (allocentric) in the hippocampal formation is as yet unknown. By simultaneously recording from a large population of neurons in the two areas we are addressing some of these questions.

Related publications:

Saleem, Harris, Carandini, Submitted

 

 

 


Vision during movement

Vision is one of the most commonly studied areas of the brain. However, our understanding of vision is limited to when one is sitting in a fixed spot. Little is know about vision during movements such as walking or navigation.

Related publications:

Saleem et al, Nat Neuro, 2013

Ayaz et al, Curr Biol, 2013

Saleem et al, Submitted


Image taken in the backwaters of Kerala, India 

Image taken in the backwaters of Kerala, India 

Innate visual behaviour

Related publications:

G De Franceschi, T Vivattanasarn, A B Saleem*, S G Solomon*, Current Biology, 2016


Image from Olafsdottir et al, eLife, 2015

Image from Olafsdottir et al, eLife, 2015

Memory replay and sleep

Related publications:
H F Olafsdottir*, C J Barry*, A B Saleem, D Hassibis, H Spiers, Hippocampal place cells construct reward related sequences through unexplored space. eLife (2015).


Image from Rossant et al, Nature Neuroscience, 2016 

Image from Rossant et al, Nature Neuroscience, 2016 

Neural coding in populations

With new technologies we now are able to record simultaneously from large populations of neurons from single or multiple areas. Part of our research focus is to understand how signals regarding the world are encoded by populations of neurons.

Related publications:

Rossant, Kadir, et al, 

Saleem, et al, Nat Neuro, 2013; 

Benucci et al, Nat Neuro, 2013; 

Busse et al, J Neurosci, 2011; 

Schovinck et al, J Neurosci., 2015